Publications

Publications

Covid-19

A trimeric human angiotensin converting enzyme 2 as an anti-SARS-CoV-2 agent

cAMP ELISA Kit

Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification

Non Wash Calcium Dye Kit for Cardiomyocytes

Determination of Pro-arrhythmic Effects of Compounds in Human iPSC-Derived Cardiomyocytes Using RDSS/μCell Imaging Platform

Use of FDSS/μCell imaging platform for preclinical cardiac electrophysiology safety screening of compounds in human induced pluripotent stem cell-derived cardiomyocytes

PDE Cell Based Assay

A Cell-based PDE4 Assay in 1536-well Plate format for High Throughput Screening

A Novel Cell Based Assay for PDE Inhibitor Screenings

Development of a Novel PDE10A Cell Based Assay

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors

Novel Cell-based Phosphodiesterase Assays

Stable Cell Line Service

Effect of the cytoplasmic domain on antigenic characteristics of HIV-1 envelope glycoprotein

ACTOne-GPCR

Commensal bacteria make GPCR ligands that mimic human signalling molecules

Validation of a new ACTOne – FLIPR assay for measurement of peptide activity in plasma samples

Selective and Brain Penetrant Neuropeptide Y Y2 Receptor Antagonists Discovered by Whole-Cell High-Throughput Screening

Application of the BD ACTOneTM Technology for the High-Throughput Screening of Gs-Coupled Receptor Antagonists

Functional analysis of endogenous β-adrenergic receptor through fluorimetric monitoring of cyclic nucleotide-gated ion channel

Miniaturized Whole Cell-based GPCR cAMP Assay Using a Novel Detection System

Glutamate Is a Positive Autocrine Signal for Glucagon Release

New Applications of GPCR Analysis using BD ACTOne Technology

Act One: A Novel Real-time cAMP Assay using the FLIPR

Analysis of Gi-Coupled Receptors with BD ACTOne Technology

Miniaturized Cyclic Nucleotide-Gated (CNG) Channel Assays to Discover Neuropeptide Y Receptor Modulators

Quantitative High-Throughput Screening Using a Live-Cell cAMP Assay Identifies Small-Molecule Agonists of the TSH Receptor

Applications of multiplex cAMP and label-free assays using FDSS7000 and EPIC BT for studying potential biased signaling through the 5-HT7 receptor

M-MPI Dye Kit

Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential

Novel In Vitro Dye Based High-Throughput Toxicity Assay on Human Primary Cells

Application of a homogenous membrane potential assay to assess mitochondrial function